Serotonin 5HT3-Receptor Antagonist for Cisplatin-Induced Nausea and Vomiting.

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The serotonin type 3 receptor antagonist BRL 43694 and nausea and vomiting induced by cisplatin.

ment was not successful, and possibly a longer duration of transplacental treatment would have been more appropriate. In our series the Wolff-Parkinson-White syndrome as the underlying cause of the tachycardia was found in three of the 22 infants who had a postnatal electrocardiogram. In summary p, ,hological atrial tachycardias are a potential cause of non-immune hydrops. As these rhythm distu...

متن کامل

Evaluation of a Neurokinin-1 Antagonist in Preventing Multiple-day Cisplatin-induced Nausea and Vomiting

Objective To perform a prospective non-randomized comparison of the effectiveness and safety of combined neurokinin-1 antagonist aprepitant treatment with the standard multiple-day cisplatin regimen for the prevention of cisplatin-induced nausea and vomiting (CINV). Methods Patients being administered 3-day cisplatin-based chemotherapy (25 mg/m2/d) who had never received aprepitant were given...

متن کامل

Effects of Pluchea lanceolata Root Extract on Cisplatin induced Nausea and Vomiting in Rat Pica Model

Cisplatin is an effective chemotherapeutics against a wide range of cancers. However, it causes significant nausea and vomiting which limit its usefulness. In the present study, the effects of methanolic root extract of Pluchea lanceolata (DC.) C. B. Clarke , asteraceae ( MPL ) was investigated against cisplatin-induced nausea using a rat pica model. In rat pica model, rats react to cispla...

متن کامل

Casopitant: a novel NK1-receptor antagonist in the prevention of chemotherapy-induced nausea and vomiting

Chemotherapy-induced nausea and vomiting (CINV) are among the most feared and distressing symptoms experienced by patients with cancer. The knowledge of the pathogenesis and neuropharmacology of CINV has expanded enormously over the last decades, the most significant discoveries being the role of 5-hydroxytryptamine (5-HT)(3)- and neurokinin (NK)(1) receptors in the emetic reflex arch. This has...

متن کامل

Chemotherapy-induced nausea and vomiting.

younger patient age, platinumor anthracyclinebased chemotherapy, low alcohol consumption, earlier cycles of chemotherapy, previous history of morning sickness, and prior emetic episodes after chemotherapy. The acute and delayed scoring systems both had good predictive accuracy when applied to the external validation sample (acute— auroc: 0.69; 95% confidence interval: 0.59 to 0.79; delayed—auro...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Practica Oto-Rhino-Laryngologica

سال: 1995

ISSN: 1884-4545,0032-6313

DOI: 10.5631/jibirin.88.1101